Defective Mucosal Movement at the Gastroesophageal Junction in Patients with Gastroesophageal Reflux Disease

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Relevance of Position and Movement of the Gastroesophageal Junction in Gastroesophageal Reflux Disease

TO THE EDITOR: Gastroesophageal reflux disease (GERD) and its complications are increasingly recognized in many parts of Asia, largely due to an increasing prevalence of obesity. Obese subjects are found to have frequent transient lower esophageal sphincter (LES) relaxations (TLESRs) and more likely to reflux with underlying mechanisms being unclear. Besides the circular muscle, recent evidence...

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Relevance of Position and Movement of the Gastroesophageal Junction in Gastroesophageal Reflux Disease: Author's Reply

TO THE EDITOR: I appreciate the interest and comments on our paper, which was published in the July 2013 issue of this journal. As you have commented, hiatus hernia is an important factor in the pathogenesis of gastroesophageal reflux disease (GERD). Especially, the elderly patients with GERD have high possibility for accompanying hiatus hernia. Our study was performed in 9 patients with GERD a...

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Endoscopic observations around the gastroesophageal junction in patients with symptomatic gastroesophageal reflux disease in South Asia.

INTRODUCTION We studied the inter-relationships of endoscopic findings around the gastroesophageal junction in patients with symptomatic gastroesophageal reflux. METHODS Data were collected with regard to hiatus hernia (HH), columnar-lined esophagus (CLE), reflux esophagitis (RE) and gastroesophageal flap valve (GEFV), prospectively from 1,150 patients who underwent diagnostic upper gastroint...

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Cow’s Milk Sensitization in Young Children with Gastroesophageal Reflux Disease

Introduction:: Recent reports have suggested that gastroesophageal reflux disease (GERD) is link with cow’s milk allergy (CMA) in children. The aim of this study was to determine the frequency of CMA in young children with GERD.Materials and Methods: This cross- sectional study included 33 children (median age, 2.93±1.90 years) with GERD according to a valid gastroesophageal reflux questionnair...

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Esophagogastric Junction Contractility Integral Reflect the Anti-reflux Barrier Dysfunction in Patients with Gastroesophageal Reflux Disease

Background/Aims Anti-reflux barrier dysfunction is one of the primary mechanisms in gastroesophageal reflux disease (GERD) pathogenesis. The esophagogastric junction contractile integral (EGJ-CI) is a new metric adopted to evaluate the EGJ contractility, which implies the antireflux barrier function. The aim of the current study was to validate this new metric in patients with GERD and its corr...

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ژورنال

عنوان ژورنال: Digestive Diseases and Sciences

سال: 2014

ISSN: 0163-2116,1573-2568

DOI: 10.1007/s10620-014-3091-9